Alcohol intolerance can cause immediate, unpleasant reactions after you consume alcohol. The most common signs and symptoms of alcohol intolerance are nasal congestion and skin flushing. This condition is sometimes inaccurately referred to as an alcohol allergy. Alcohol intolerance is caused by a genetic condition in which the body is unable to break down alcohol. The only way to prevent alcohol intolerance is to avoid alcohol altogether.
In some cases, what may seem to be alcohol intolerance is caused by a reaction to something else in an alcoholic beverage — such as chemicals, grains or preservatives. In other cases, reactions are caused by combining alcohol with certain medications. In rare instances, reactions to alcohol can be a sign of a serious underlying health problem that requires diagnosis and treatment.
Alcohol intolerance symptoms — or symptoms of a reaction to ingredients in an alcoholic beverage — can include:
When to see a doctor
Alcohol intolerance occurs when your body doesn't have the proper enzymes to break down (metabolize) the toxins in alcohol. This is caused by inherited (genetic) traits.
Intolerance reactions can also be caused by a number of other ingredients commonly found in alcoholic beverages, especially in beer or wine. These include:
In some cases, reactions can be triggered by an allergy to a grain such as corn, wheat or rye or to another substance contained in alcoholic beverages.
Rarely, severe pain after drinking alcohol is a sign of a more serious underlying disorder, such as Hodgkin lymphoma.
Risk factors for alcohol intolerance or other reactions to alcoholic beverages include:
Depending on the cause, complications of alcohol intolerance or other reactions to alcoholic beverages can include:
Preparing for your appointment
Although alcohol intolerance usually isn't a serious issue, you may want to discuss it with your doctor at your next appointment. Because appointments can be brief, it's a good idea to prepare ahead of time. Here's some information to help you get ready for your appointment, and what to expect from your doctor.
Questions to ask your doctor
Don't hesitate to ask questions during your appointment any time that you don't understand something.
What to expect from your doctor
What you can do in the meantime
Tests and diagnosis
Your doctor will try to figure out whether you have an intolerance, or if your symptoms are caused by something else, such as a reaction to other ingredients in alcoholic beverages. The following may help determine the cause of your symptoms:
Treatments and drugs
The only way to avoid alcohol intolerance symptoms or an allergic reaction is to avoid alcohol or the particular beverage or ingredients that cause the problem. For a minor reaction, over-the-counter or prescription antihistamines may help reduce symptoms, such as itching or hives. However, antihistamines can't treat a serious allergic reaction.
If you've had a severe allergic reaction to a certain food, wear a medical alert bracelet or necklace that lets others know that you have an allergy in case you have a reaction and you're unable to communicate. Ask your doctor if you need to carry emergency epinephrine (adrenaline) in the form of an autoinjector (EpiPen, Twinject). This prescription device has a concealed needle that injects a single dose of epinephrine when you press it against your thigh.
Unfortunately, no medications or other treatments can prevent reactions to alcohol or other ingredients in alcoholic beverages. The only way to avoid a reaction is to avoid alcohol completely or avoid whatever particular substance causes your reaction. Read beverage labels carefully to see whether they contain ingredients or additives you know cause a reaction, such as sulfites or certain grains. But, be aware that labels may not list the ingredient or ingredients that cause your reaction.
The key treatment is to do your best to avoid the beverage in question. Work with your doctor to identify what steps you can take to relieve your symptoms and how to spot and respond to a severe reaction.
Last Updated: 2012-04-26
© 1998-2016 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.com," "Mayo Clinic Health Information," "Reliable information for a healthier life" and the triple-shield Mayo logo are trademarks of Mayo Foundation for Medical Education and Research.
Terms and conditions of use